JDD Special Focus

Acne Supplements

Stay up-to-date on new clinical findings on Acne. View the latest articles, case reports, editorial features, supplements, Podcast episodes and more!

 

Supplements

Acneceuticals Maximized Therapeutic Outcomes in a Real-World Setting

Acne is the most common cutaneous disease worldwide and the most frequent disorder to present to the dermatology practice. Although efficacious treatments exist, clinicians continue to search for better regimens with improved safety for our patients. 

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Topical Acne Treatment: What’s Behind the Scenes in 2024

Optimal topical acne treatments should ideally target multiple pathways involved in acne development.2  Traditional treatments, though often effective, may come with limitations such as skin irritation, dryness, or other adverse effects. Thus, the pursuit of optimal topical acne treatments is critical to enhancing efficacy, minimizing side effects, and improving patient adherence and satisfaction.

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Advancements in Topical Combination Products for Acne Treatment

Antibiotic resistance and treatment adherence remain significant challenges for acne treatment. Advances in topical formulations have ushered in an era of fixed combination topical therapeutics that are well-tolerated and more efficacious. In addition, their once-daily application leads to increased treatment adherence. This article discusses formulation strategies that allow for the coadministration of active drugs and reviews all commercially available fixed-combination topical acne treatments.

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Tretinoin Formulation: From Microsponges to Polymeric Emulsion

The history of tretinoin and its use in dermatology is a testament both to the drug’s well-established efficacy and its potential to cause skin irritation. Over more than four decades, the drug that launched the retinoid class into the market has been used in the topical management of acne, either alone or in combination.

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Targeting Acne Pathogenesis with Topical Therapies

We, as dermatologists, are exceedingly lucky.  We can watch our patients improve before our eyes. In clinical practice, we don’t often track a quantitative metric to gauge success but rather measure the success of our treatment by the appearance of our patients’ skin.

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Podcast Episodes

Ask the Investigator: Acne, OCPs, and a Side Order of Practical Pearls for the Adolescent Patient

JDD Podcast host Dr. Adam Friedman gets first-hand insight from internationally acclaimed pediatric dermatologist Dr. Lawrence Eichenfield on his recent study entitled “Hormonal Contraceptives and Acne: A Retrospective Analysis of 2147 Patients” published in the June 2016 edition of the Journal of Drugs of Dermatology. Want a refresher on the use of OCPs in Acne?

Interested in learning how to initiate a patient based survey study? Just curious how a leader in the field gets an uninterested adolescent to be compliant and engaged in his/her acne care? These are just a few of the practical pearls provided.

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Featured Case Report

Efficacy and Safety of Sarecycline, a Novel, Once-Daily, Narrow Spectrum Antibiotic for the Treatment of Moderate to Severe Facial Acne Vulgaris: Results of a Phase 2, Dose-Ranging Study

There is a need for new oral antibiotics for acne with improved safety profiles and targeted antibacterial spectra. Sarecycline is a novel, tetracycline-class antibiotic specifically designed for acne, offering a narrow spectrum of activity compared with currently available tetracyclines, including less activity against enteric Gram-negative bacteria. This phase 2 study evaluated the efficacy and safety of three doses of sarecycline for moderate to severe facial acne vulgaris.

 

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Featured Editorial

Virtual Exams No Substitute for In-Person Care of Acne and Rosacea

Some dermatologists may be surprised to hear that the concept of teledermatology originated 25 years ago, and has slowly increased in usage, primarily for the purpose of providing care to those in underserved areas.1 The challenges created by the COVID19 pandemic has rapidly accelerated both interest and usage of telemedicine by dermatologists, with the American Academy of Dermatology and other dedicated groups responding quickly to provide guidance on how to integrate teledermatology into real-world dermatology practice effectively, and hopefully with avoidance of technical, medicolegal, and financial pitfalls.2
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Dermatology News

Atopic DermatitisFeatured ArticlesHidradenitis SuppurativaLatest NewsPsoriasisVitiligoRacial and Ethnic Representation in Clinical Trials of Janus Kinase Inhibitors for Dermatologic Conditions: A Systematic Review
May 4, 2026

Racial and Ethnic Representation in Clinical Trials of Janus Kinase Inhibitors for Dermatologic Conditions: A Systematic Review

JDD analysis highlights racial gaps in JAK inhibitor dermatology trials Have you caught this new JDD, analysis on JAK inhibitor trials? Dermatologists and clinical investigators will likely find this review relevant…
Journal of Drugs in Dermatology JDD featuring Alopecia Areata: The Clinician and Patient VoiceFeatured ArticlesLatest NewsSkin CancerPatients With Lichen Planopilaris Are at Increased Risk of Skin Cancer
May 1, 2026

Patients With Lichen Planopilaris Are at Increased Risk of Skin Cancer

JDD alert: Must-read study reports an association between lichen planopilaris and scalp non-melanoma skin cancer A new JDD report analyzes global TriNetX data from 2005 to 2025 and compares patients…
Featured ArticlesLatest NewsPodcast HighlightsSufficiently Insufficient to Support Steroid Stewardship
May 1, 2026

Sufficiently Insufficient to Support Steroid Stewardship

Guest: Dr. Rachel Sheskier Steroids: indispensable, unpredictable, and, when it comes to endocrinology, often hiding in plain sight. In this episode of the JDD Podcast, Dr. Adam Friedman continues the…
Dermatology RoundupFeatured ArticlesLatest NewsDermatology Roundup: AAD Research Highlights
April 30, 2026

Dermatology Roundup: AAD Research Highlights

New JDD study examines a combined regimen for PIH in skin of color The American Academy of Dermatology’s Annual Meeting is always a hubbub of the latest dermatology research. The…